TXNDC6 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q86XW9 |
| Other Accession | NP_835231.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36856 Da |
| Antigen Region | 111-139 aa |
| Gene ID | 347736 |
|---|---|
| Other Names | Thioredoxin domain-containing protein 6, Thioredoxin-like protein 2, Txl-2, NME9, TXL2, TXNDC6 |
| Target/Specificity | This TXNDC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the Central region of human TXNDC6. |
| Dilution | IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TXNDC6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NME9 (HGNC:21343) |
|---|---|
| Synonyms | TXL2, TXNDC6 |
| Function | May be a regulator of microtubule physiology. |
| Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:A0A1L1SUL6}. Dynein axonemal particle {ECO:0000250|UniProtKB:Q6IRC5}. Note=Associated with microtubules Detected in cilia of lung epithelium, and associated with the spermatid tail and manchette. {ECO:0000250|UniProtKB:A0A1L1SUL6} |
| Tissue Location | Detected at very low levels in testis, lung and brain. |

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Provided below are standard protocols that you may find useful for product applications.
Background
May be a regulator of microtubule physiology.
References
Lee, E.J., et al. Chest 135(2):344-352(2009)
Desvignes, T., et al. BMC Evol. Biol. 9, 256 (2009) :
Miranda-Vizuete, A., et al. Antioxid. Redox Signal. 6(1):25-40(2004)
Sadek, C.M., et al. J. Biol. Chem. 278(15):13133-13142(2003)
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