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CCDC39 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UFE4 |
| Other Accession | NP_852091.1 |
| Reactivity | Human, Hamster, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 109901 Da |
| Antigen Region | 770-798 aa |
| Gene ID | 339829 |
|---|---|
| Other Names | Coiled-coil domain-containing protein 39, CCDC39 |
| Target/Specificity | This CCDC39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 770-798 amino acids from the C-terminal region of human CCDC39. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CCDC39 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CCDC39 (HGNC:25244) |
|---|---|
| Function | Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella (PubMed:21131972). Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly (PubMed:21131972). |
| Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme. Note=CCDC40 is required for localization to axonemes. |
| Tissue Location | Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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