SFR1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, FC, E |
|---|---|
| Primary Accession | Q86XK3 |
| Other Accession | NP_660290.3, NP_001002759.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 28262 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 119392 |
|---|---|
| Other Names | Swi5-dependent recombination DNA repair protein 1 homolog, Meiosis protein 5 homolog, SFR1, C10orf78, MEI5, MEIR5 |
| Target/Specificity | This C10orf78 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human C10orf78. |
| Dilution | WB~~1:1000 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SFR1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SFR1 |
|---|---|
| Synonyms | C10orf78, MEI5, MEIR5 |
| Function | Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination (PubMed:21252223). Acts as a transcriptional modulator for ESR1 (PubMed:23874500). |
| Cellular Location | Nucleus. Note=Colocalizes with ESR1 in the nucleus |
| Tissue Location | Widely expressed.. |

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Provided below are standard protocols that you may find useful for product applications.
References
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
Gubin, A.N., et al. Genomics 59(2):168-177(1999)
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