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ACAP1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q15027 |
| Other Accession | Q8K2H4, NP_055531.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 81536 Da |
| Antigen Region | 96-125 aa |
| Gene ID | 9744 |
|---|---|
| Other Names | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1, Centaurin-beta-1, Cnt-b1, ACAP1, CENTB1, KIAA0050 |
| Target/Specificity | This ACAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the N-terminal region of human ACAP1. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ACAP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ACAP1 |
|---|---|
| Synonyms | CENTB1, KIAA0050 |
| Function | GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration. |
| Cellular Location | Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side |
| Tissue Location | Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Cuthbert, E.J., et al. Am. J. Physiol., Cell Physiol. 294 (1), C263-C270 (2008) :
Li, J., et al. J. Cell Biol. 178(3):453-464(2007)
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Shinozaki-Narikawa, N., et al. Traffic 7(11):1539-1550(2006)
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