GPR142 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| FC, WB, E |
|---|---|
| Primary Accession | Q7Z601 |
| Other Accession | NP_861455.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 51106 Da |
| Antigen Region | 86-114 aa |
| Gene ID | 350383 |
|---|---|
| Other Names | Probable G-protein coupled receptor 142, G-protein coupled receptor PGR2, GPR142, PGR2 |
| Target/Specificity | This GPR142 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the N-terminal region of human GPR142. |
| Dilution | FC~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GPR142 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GPR142 |
|---|---|
| Synonyms | PGR2 |
| Function | Orphan receptor. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Exclusively expressed in the central nervous system, most abundantly in the ventrolateral region of caudate putamen, the habenular nucleus, the zona incerta, and the medial mammillary nucleus. |

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Provided below are standard protocols that you may find useful for product applications.
Background
GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).
References
Matsuo, A., et al. Biochem. Biophys. Res. Commun. 331(1):363-369(2005)
Fredriksson, R., et al. FEBS Lett. 554(3):381-388(2003)
Vassilatis, D.K., et al. Proc. Natl. Acad. Sci. U.S.A. 100(8):4903-4908(2003)
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