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SAMD7 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q7Z3H4 |
| Other Accession | NP_872416.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 49112 Da |
| Antigen Region | 202-230 aa |
| Gene ID | 344658 |
|---|---|
| Other Names | Sterile alpha motif domain-containing protein 7, SAM domain-containing protein 7, SAMD7 |
| Target/Specificity | This SAMD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-230 amino acids from the Central region of human SAMD7. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SAMD7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SAMD7 |
|---|---|
| Function | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, essential for establishing rod photoreceptor cell identity and function by silencing nonrod gene expression in developing rod photoreceptor cells. Via its association with the PRC1-like complex, promotes epigenetic repressive marks H3K27me3 and H2AK119ub marks in nonrod genes, silencing their transcription. Represses Crx-controlled photoreceptor-specific gene expression. |
| Cellular Location | Nucleus. Cytoplasm {ECO:0000250|UniProtKB:Q8C8Y5}. Note=Co-localizes with PHC2 and RNF2 in nuclear polycomb bodies. {ECO:0000250|UniProtKB:Q8C8Y5} |
| Tissue Location | Expressed in the retina (at protein level) (PubMed:26887858). Expressed in the retinal inner and outer nuclear layers (PubMed:38272031). |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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$ 150.00
$ 385.00
Cat# AP11411c
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