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TTLL13 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, E |
|---|---|
| Primary Accession | A6NNM8 |
| Other Accession | NP_001025135.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 93645 Da |
| Antigen Region | 461-490 aa |
| Other Names | Tubulin polyglutamylase TTLL13, 6---, Tubulin--tyrosine ligase-like protein 13, TTLL13 {ECO:0000312|Ensembl:ENSP00000345294} |
|---|---|
| Target/Specificity | This TTLL13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 461-490 amino acids from the Central region of human TTLL13. |
| Dilution | WB~~1:1000 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TTLL13 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TTLL13 (HGNC:32484) |
|---|---|
| Synonyms | TTLL13P |
| Function | Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin. Mediates ATP-dependent polyglutamate side-chain elongation of the polyglutamylation reaction but not the initiation step. Preferentially modifies the alpha-tubulin tail over a beta-tail. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Polyglutamylase which preferentially modifies alpha-tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (By similarity).
References
Janke, C., et al. Science 308(5729):1758-1762(2005)
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