NUDT19 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, E |
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Primary Accession | A8MXV4 |
Other Accession | NP_001099040.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 42233 Da |
Antigen Region | 153-181 aa |
Gene ID | 390916 |
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Other Names | Nucleoside diphosphate-linked moiety X motif 19, mitochondrial, Nudix motif 19, 361-, NUDT19 |
Target/Specificity | This NUDT19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-181 amino acids from the Central region of human NUDT19. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | NUDT19 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NUDT19 |
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Function | Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'- bisphosphate (By similarity). Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty- acyl-CoA esters are the primary substrates (By similarity). Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters (By similarity). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity). |
Cellular Location | Peroxisome {ECO:0000250|UniProtKB:P11930}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Coenzyme A diphosphatase that mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters. At low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity).
References
Ofman, R., et al. Biochem. J. 393 (PT 2), 537-543 (2006) :
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