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RRAS Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P10301 |
| Other Accession | P10833, NP_006261.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 23480 Da |
| Antigen Region | 91-123 aa |
| Gene ID | 6237 |
|---|---|
| Other Names | Ras-related protein R-Ras, p23, RRAS |
| Target/Specificity | This RRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-123 amino acids from the Central region of human RRAS. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RRAS Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RRAS |
|---|---|
| Function | GTP-binding protein with GTPase activity, likely involved in the regulation of MAPK signaling pathway and thereby controlling multiple cellular processes (PubMed:39809765). Regulates the organization of the actin cytoskeleton (PubMed:16537651, PubMed:18270267). With OSPBL3, modulates integrin beta-1 (ITGB1) activity (PubMed:18270267). |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Inner surface of plasma membrane possibly with attachment requiring acylation of the C- terminal cysteine (By similarity with RAS) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
RRAS regulates the organization of the actin cytoskeleton.
References
Sakurai, A., et al. Mol. Cell. Biol. 30(12):3086-3098(2010)
Tong, Y., et al. J. Biol. Chem. 284(51):35962-35972(2009)
Inuzuka, T., et al. Biochem. Biophys. Res. Commun. 379(2):510-513(2009)
Xu, L., et al. J. Biol. Chem. 284(5):2706-2718(2009)
Hodkinson, P.S., et al. J. Biol. Chem. 282(39):28991-29001(2007)
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