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OGN Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, FC, WB, E |
|---|---|
| Primary Accession | P20774 |
| Other Accession | P19879, NP_148935.1, NP_054776.1 |
| Reactivity | Human |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 33922 Da |
| Antigen Region | 246-276 aa |
| Gene ID | 4969 |
|---|---|
| Other Names | Mimecan, Osteoglycin, Osteoinductive factor, OIF, OGN, OIF, SLRR3A |
| Target/Specificity | This OGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-276 amino acids from the C-terminal region of human OGN. |
| Dilution | WB~~1:500 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | OGN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | OGN |
|---|---|
| Synonyms | OIF, SLRR3A |
| Function | Induces bone formation in conjunction with TGF-beta-1 or TGF- beta-2. |
| Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q8MJF1} |
| Tissue Location | Bone. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein which induces ectopic bone formation in conjunction with transforming growth factor beta. This protein is a small proteoglycan which contains tandem leucine-rich repeats (LRR). Alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq].
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Dimasi, D.P., et al. Mol. Vis. 16, 562-569 (2010) :
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
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