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UNQ9391 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q6UWB4 |
| Other Accession | NP_940866.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 38856 Da |
| Antigen Region | 289-318 aa |
| Gene ID | 203074 |
|---|---|
| Other Names | Serine protease 55, 3421-, Testis serine protease 1, T-SP1, PRSS55, TSP1 |
| Target/Specificity | This UNQ9391 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-318 amino acids from the C-terminal region of human UNQ9391. |
| Dilution | FC~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UNQ9391 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PRSS55 |
|---|---|
| Synonyms | TSP1 {ECO:0000303|PubMed:18844450} |
| Function | Probable serine protease, which plays a crucial role in the fertility of male mice including sperm migration and sperm-egg interaction. |
| Cellular Location | [Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q14BX2}. Cytoplasm, cytosol. Note=Mainly found in the membrane part of the cells and only in small amounts in the cytosol |
| Tissue Location | Only detected in testis. Expressed in spermatogonia, spermatocytes, spermatids, Leydig and Sertoli cells Expressed in prostate cancer and ovarian cancer (at protein level) |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of a group of membrane-anchored chymotrypsin (S1)-like serine proteases. The enocoded protein is primarily expressed in the Leydig and Sertoli cells of the testis and may be involved in male fertility. Alternate splicing results in multiple transcript variants.
References
Neth, P., et al. Biol. Chem. 389(12):1495-1504(2008)
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