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FRAT2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, IHC-P, E |
|---|---|
| Primary Accession | O75474 |
| Other Accession | NP_036215.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 24051 Da |
| Antigen Region | 203-230 aa |
| Gene ID | 23401 |
|---|---|
| Other Names | GSK-3-binding protein FRAT2, Frequently rearranged in advanced T-cell lymphomas 2, FRAT-2, FRAT2 |
| Target/Specificity | This FRAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-230 amino acids from the C-terminal region of human FRAT2. |
| Dilution | IF~~1:10~50 WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FRAT2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FRAT2 |
|---|---|
| Function | Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression.
References
Lee, D.Y., et al. Menopause 17(5):1064-1070(2010)
Liu, G.P., et al. Neurobiol. Aging 29(9):1348-1358(2008)
Stoothoff, W.H., et al. J. Biol. Chem. 280(1):270-276(2005)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
Freemantle, S.J., et al. Gene 291 (1-2), 17-27 (2002) :
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