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> home > Products > Primary Antibodies > Antibody Collections > Catalog Updated > FOLR4 Antibody (N-term)
FOLR4 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | A6ND01 |
| Other Accession | NP_001186135.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 28672 Da |
| Antigen Region | 17-47 aa |
| Gene ID | 390243 |
|---|---|
| Other Names | Sperm-egg fusion protein Juno, Folate receptor 4, Folate receptor delta, FR-delta, IZUMO1 receptor protein JUNO, IZUMO1R (HGNC:32565), FOLR4, JUNO |
| Target/Specificity | This FOLR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human FOLR4. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FOLR4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IZUMO1R (HGNC:32565) |
|---|---|
| Function | Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion (PubMed:30517645). The ligand- receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate. |
| Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9EQF4}. Cell projection, microvillus membrane; Lipid- anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9EQF4}. Note=GPI-anchored at the oolemma microvilli. {ECO:0000250|UniProtKB:Q9EQF4} |
| Tissue Location | Expressed in unfertilized oocytes (at protein level). |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Folate receptor 4 is a highly expressed cell surface marker of regulatory T cells.
References
Spiegelstein, O., et al. Gene 258 (1-2), 117-125 (2000) :
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$ 150.00
$ 385.00
Cat# AP11990a
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