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RBPJL Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | Q9UBG7 |
| Other Accession | NP_055091.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 56751 Da |
| Antigen Region | 8-36 aa |
| Gene ID | 11317 |
|---|---|
| Other Names | Recombining binding protein suppressor of hairless-like protein, Transcription factor RBP-L, RBPJL, RBPL, RBPSUHL |
| Target/Specificity | This RBPJL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human RBPJL. |
| Dilution | WB~~1:2000 FC~~1:10~50 IHC-P~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RBPJL Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RBPJL |
|---|---|
| Synonyms | RBPL, RBPSUHL |
| Function | Putative transcription factor, which cooperates with EBNA2 to activate transcription. |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). The protein encoded by this gene is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.
References
Beres, T.M., et al. Mol. Cell. Biol. 26(1):117-130(2006)
Deloukas, P., et al. Nature 414(6866):865-871(2001)
Nakagawa, H., et al. Oncogene 19(2):210-216(2000)
Tani, S., et al. J. Hum. Genet. 44(1):73-75(1999)
Minoguchi, S., et al. Mol. Cell. Biol. 17(5):2679-2687(1997)
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