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FTSJ3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IY81 |
| Other Accession | NP_060117.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 96558 Da |
| Antigen Region | 616-646 aa |
| Gene ID | 117246 |
|---|---|
| Other Names | pre-rRNA processing protein FTSJ3 {ECO:0000255|HAMAP-Rule:MF_03163}, 211- {ECO:0000255|HAMAP-Rule:MF_03163}, 2'-O-ribose RNA methyltransferase SPB1 homolog {ECO:0000255|HAMAP-Rule:MF_03163}, Protein ftsJ homolog 3 {ECO:0000255|HAMAP-Rule:MF_03163}, Putative rRNA methyltransferase 3 {ECO:0000255|HAMAP-Rule:MF_03163}, FTSJ3 {ECO:0000255|HAMAP-Rule:MF_03163} |
| Target/Specificity | This FTSJ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 616-646 amino acids from the Central region of human FTSJ3. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FTSJ3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FTSJ3 {ECO:0000255|HAMAP-Rule:MF_03163} |
|---|---|
| Function | RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. |
| Cellular Location | Nucleus, nucleolus {ECO:0000255|HAMAP- Rule:MF_03163, ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:22195017} |
Provided below are standard protocols that you may find useful for product applications.
Background
Although the function of this gene is not known, the existence of this gene is supported by mRNA and EST data. A possible function of the encoded protein can be inferred from amino acid sequence similarity to the E.coli FtsJ protein and to a mouse protein possibly involved in embryogenesis.
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002)
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