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PCYT1A Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IF, IHC-P, WB, E |
|---|---|
| Primary Accession | P49585 |
| Other Accession | P19836, P49586, P49584, NP_005008.2 |
| Reactivity | Human |
| Predicted | Hamster, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 41731 Da |
| Antigen Region | 27-54 aa |
| Gene ID | 5130 |
|---|---|
| Other Names | Choline-phosphate cytidylyltransferase A, CCT-alpha, CTP:phosphocholine cytidylyltransferase A, CCT A, CT A, Phosphorylcholine transferase A, PCYT1A, CTPCT, PCYT1 |
| Target/Specificity | This PCYT1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human PCYT1A. |
| Dilution | IF~~1:10~50 IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PCYT1A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PCYT1A |
|---|---|
| Synonyms | CTPCT, PCYT1 |
| Function | Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis. |
| Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:P19836}. Membrane {ECO:0000250|UniProtKB:P19836}; Peripheral membrane protein {ECO:0000250|UniProtKB:P19836}. Endoplasmic reticulum membrane; Peripheral membrane protein {ECO:0000250|UniProtKB:P19836}. Nucleus Note=It can interconvert between an inactive cytosolic form and an active membrane-bound form. {ECO:0000250|UniProtKB:P19836} |
| Tissue Location | Brain, placenta, liver, fetal and adult lung. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
PCYT1A controls phosphatidylcholine synthesis.
References
Mostowska, A., et al. J. Med. Genet. (2010) In press :
Mostowska, A., et al. Eur. J. Oral Sci. 118(4):325-332(2010)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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