Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
TBPL2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IF, IHC-P, WB, E |
|---|---|
| Primary Accession | Q6SJ96 |
| Other Accession | NP_950248.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 38035 Da |
| Antigen Region | 12-39 aa |
| Gene ID | 387332 |
|---|---|
| Other Names | TATA box-binding protein-like protein 2, TBP-like protein 2, TATA box-binding protein-related factor 3, TBP-related factor 3, TBPL2 {ECO:0000312|EMBL:AAI171861, ECO:0000312|HGNC:HGNC:19841} |
| Target/Specificity | This TBPL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human TBPL2. |
| Dilution | IF~~1:10~50 IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TBPL2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TBPL2 {ECO:0000312|EMBL:AAI17186.1, ECO:0000312|HGNC:HGNC:19841} |
|---|---|
| Function | Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity). |
| Cellular Location | Cytoplasm. Nucleus. Note=Present in the cytoplasm during cytokinesis. |
| Tissue Location | Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
TBPL2 is a transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity).
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Deato, M.D., et al. Genes Dev. 21(17):2137-2149(2007)
Di Pietro, C., et al. DNA Cell Biol. 26(6):369-385(2007)
Persengiev, S.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(25):14887-14891(2003)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
