KRTAP13-3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, WB, E |
---|---|
Primary Accession | Q3SY46 |
Other Accession | NP_853653.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 19236 Da |
Antigen Region | 13-3 aa |
Gene ID | 337960 |
---|---|
Other Names | Keratin-associated protein 13-3, KRTAP13-3, KAP133 |
Target/Specificity | This KRTAP13-3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-135 amino acids from the C-terminal region of human KRTAP13-3. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | KRTAP13-3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KRTAP13-3 |
---|---|
Synonyms | KAP13.3 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity). |
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Provided below are standard protocols that you may find useful for product applications.
Background
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity).
References
Rogers, M.A., et al. J. Biol. Chem. 277(50):48993-49002(2002)
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