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DNAJC27 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9NZQ0 |
| Other Accession | NP_057628.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 30855 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 51277 |
|---|---|
| Other Names | DnaJ homolog subfamily C member 27, Rab and DnaJ domain-containing protein, DNAJC27, RABJS, RBJ |
| Target/Specificity | This DNAJC27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DNAJC27. |
| Dilution | IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DNAJC27 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DNAJC27 |
|---|---|
| Synonyms | RABJS, RBJ |
| Function | GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q8CFP6}. |
| Tissue Location | Overexpressed in gastrointestinal cancers; expression correlates with later tumor-node-metastasis stages of colorectal cancers. |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Belongs to the small GTPase superfamily. Rab family. 3 isoforms.
References
Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
Nepomuceno-Silva, J.L., et al. Gene 327(2):221-232(2004)
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$ 150.00
$ 385.00
Cat# AP12755a
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