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CTSO Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P43234 |
| Other Accession | NP_001325.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 35958 Da |
| Antigen Region | 69-98 aa |
| Gene ID | 1519 |
|---|---|
| Other Names | Cathepsin O, CTSO, CTSO1 |
| Target/Specificity | This CTSO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the N-terminal region of human CTSO. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CTSO Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CTSO |
|---|---|
| Synonyms | CTSO1 |
| Function | Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover. |
| Cellular Location | Lysosome. |
| Tissue Location | Expressed in all tissues examined. High levels seen in the ovary, kidney and placenta while low levels seen in thymus and skeletal muscle |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase.
References
Roeske, D., et al. Mol. Psychiatry (2009) In press :
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Santamaria, I., et al. Genomics 53(2):231-234(1998)
Shi, G.P., et al. FEBS Lett. 357(2):129-134(1995)
Velasco, G., et al. J. Biol. Chem. 269(43):27136-27142(1994)
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