- CITATIONS: 1
|Application ||IHC-P, WB, E|
|Other Accession||Q9R1K6, NP_001091048.1|
|Calculated MW||43860 Da|
|Antigen Region||232-261 aa|
|Other Names||Probable G-protein coupled receptor 34, GPR34|
|Target/Specificity||This GPR34 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the Central region of human GPR34.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GPR34 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Broadly expressed.|
Provided below are standard protocols that you may find useful for product applications.
G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.
Engemaier, E., et al. Genomics 87(2):254-264(2006)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Jacobi, F.K., et al. Hum. Genet. 107(1):89-91(2000)
Schoneberg, T., et al. Biochim. Biophys. Acta 1446 (1-2), 57-70 (1999) :
Marchese, A., et al. Genomics 56(1):12-21(1999)
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