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ALDH3B2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P48448 |
| Other Accession | NP_001026786.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 42635 Da |
| Antigen Region | 252-280 aa |
| Gene ID | 222 |
|---|---|
| Other Names | Aldehyde dehydrogenase family 3 member B2, Aldehyde dehydrogenase 8, ALDH3B2, ALDH8 |
| Target/Specificity | This ALDH3B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-280 amino acids from the C-terminal region of human ALDH3B2. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ALDH3B2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ALDH3B2 |
|---|---|
| Synonyms | ALDH8 |
| Function | Oxidizes medium and long chain fatty aldehydes in lipid droplets into non-toxic fatty acids. |
| Cellular Location | Lipid droplet {ECO:0000250|UniProtKB:E9Q3E1}. |
| Tissue Location | Salivary gland (PubMed:8890755). Expressed at protein level in placenta (PubMed:31847104) |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. The expression of these transcripts is restricted to the salivary gland among the human tissues examined. Alternate transcriptional splice variants have been characterized.
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
Hsu, L.C., et al. Gene 189(1):89-94(1997)
Hsu, L.C., et al. Gene 174(2):319-322(1996)
Hsu, L.C., et al. Adv. Exp. Med. Biol. 372, 159-168 (1995) :
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