SLAMF8 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9P0V8 |
Other Accession | NP_064510.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 31670 Da |
Antigen Region | 256-285 aa |
Gene ID | 56833 |
---|---|
Other Names | SLAM family member 8, B-lymphocyte activator macrophage expressed, BCM-like membrane protein, CD353, SLAMF8, BLAME |
Target/Specificity | This SLAMF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-285 amino acids from the C-terminal region of human SLAMF8. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SLAMF8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SLAMF8 |
---|---|
Synonyms | BLAME |
Function | May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor. |
Cellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Location | Expressed in lymph node, spleen, thymus and bone marrow. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.
References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)
Tangye, S.G., et al. J. Immunol. 171(5):2485-2495(2003)
Kingsbury, G.A., et al. J. Immunol. 166(9):5675-5680(2001)
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