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CLTB Antibody

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CLTB Antibody AP12926a
    Western blot analysis of CLTB (arrow) using rabbit polyclonal CLTB Antibody (Cat. #AP12926a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLTB gene.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P09497
Other Accession NP_009028.1, NP_001825.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 25190 Da
Additional Information
Gene ID 1212
Other Names Clathrin light chain B, Lcb, CLTB
Target/Specificity This CLTB antibody is generated from rabbits immunized with a recombinant protein from human CLTB.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLTB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLTB
Function Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Cellular Location Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles
Research Areas
Citations (0)
citation

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Background

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Martins-de-Souza, D., et al. J Neural Transm 116(3):275-289(2009)
Loerke, D., et al. Traffic 6(10):918-929(2005)
Chen, C.Y., et al. J. Biol. Chem. 280(7):6109-6117(2005)

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$ 182.50
$ 70.00
Cat# AP12926a
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