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ELAVL2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, FC, WB, E |
|---|---|
| Primary Accession | Q12926 |
| Other Accession | Q7SZT7, O09032, Q61701, P26378, Q91584, Q60900, Q14576, Q91903, Q8CH84, Q60899, NP_001164666.1, NP_001164668.1, A0A0R4IEW8 |
| Reactivity | Human, Mouse |
| Predicted | Rat, Xenopus, Zebrafish |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 39504 Da |
| Antigen Region | 156-184 aa |
| Gene ID | 1993 |
|---|---|
| Other Names | ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, HuB, Nervous system-specific RNA-binding protein Hel-N1, ELAVL2, HUB |
| Target/Specificity | This ELAVL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human ELAVL2. |
| Dilution | IHC-P~~1:100 FC~~1:10~50 WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ELAVL2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ELAVL2 |
|---|---|
| Synonyms | HUB |
| Function | RNA-binding protein that binds to the 3' untranslated region (3'UTR) of target mRNAs (By similarity). Seems to recognize a GAAA motif (By similarity). Can bind to its own 3'UTR, the FOS 3'UTR and the ID 3'UTR (By similarity). |
| Tissue Location | Brain; neural-specific. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene.
References
Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)
Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009) :
D'Alessandro, V., et al. Cell. Oncol. 30(4):291-297(2008)
Jonson, L., et al. Mol. Cell Proteomics 6(5):798-811(2007)
Yano, M., et al. J. Biol. Chem. 280(13):12690-12699(2005)
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