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WBSCR17 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6IS24 |
| Other Accession | NP_071924.1 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 67751 Da |
| Antigen Region | 411-440 aa |
| Gene ID | 64409 |
|---|---|
| Other Names | Putative polypeptide N-acetylgalactosaminyltransferase-like protein 3, Polypeptide GalNAc transferase-like protein 3, GalNAc-T-like protein 3, pp-GaNTase-like protein 3, Protein-UDP acetylgalactosaminyltransferase-like protein 3, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3, Williams-Beuren syndrome chromosomal region 17 protein, WBSCR17, GALNTL3 |
| Target/Specificity | This WBSCR17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 411-440 amino acids from the C-terminal region of human WBSCR17. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | WBSCR17 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GALNT17 (HGNC:16347) |
|---|---|
| Function | May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. |
| Cellular Location | Golgi apparatus membrane; Single- pass type II membrane protein |
| Tissue Location | Highly expressed in brain and heart. Weakly expressed in kidney, liver, lung and spleen |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an N-acetylgalactosaminyltransferase, which has 97% sequence identity to the mouse protein. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq].
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Nakamura, N., et al. Biol. Pharm. Bull. 28(3):429-433(2005)
Merla, G., et al. Hum. Genet. 110(5):429-438(2002)
Valero, M.C., et al. Genomics 69(1):1-13(2000)
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