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CNTLN Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9NXG0 |
| Other Accession | NP_001107867.1, NP_060208.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 161571 Da |
| Antigen Region | 199-227 aa |
| Gene ID | 54875 |
|---|---|
| Other Names | Centlein, Centrosomal protein, CNTLN, C9orf101, C9orf39 |
| Target/Specificity | This CNTLN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-227 amino acids from the N-terminal region of human CNTLN. |
| Dilution | IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CNTLN Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CNTLN |
|---|---|
| Synonyms | C9orf101, C9orf39 |
| Function | Required for centrosome cohesion and recruitment of CEP68 to centrosomes. |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Colocalizes with gamma-tubulin during interphase and mitosis Appears to associate with the mother centriole during G1 phase and with daughter centrioles towards G1/S phase (By similarity). Localizes to the proximal ends of the centrioles (PubMed:24554434). Levels are high at interphase centrosomes but are reduced on mitotic spindle poles (PubMed:24554434). {ECO:0000250|UniProtKB:A9ZSY0, ECO:0000269|PubMed:24554434} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The specific function of this protein remains unknown.
References
Bailey, S.D., et al. Diabetes Care (2010) In press :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Song, H., et al. Nat. Genet. 41(9):996-1000(2009)
Makino, K., et al. Biochem. Biophys. Res. Commun. 366(4):958-962(2008)
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