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CDH22 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9UJ99 |
| Other Accession | NP_067071.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 89091 Da |
| Antigen Region | 411-440 aa |
| Gene ID | 64405 |
|---|---|
| Other Names | Cadherin-22, Pituitary and brain cadherin, PB-cadherin, CDH22, C20orf25 |
| Target/Specificity | This CDH22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 411-440 amino acids from the Central region of human CDH22. |
| Dilution | IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CDH22 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CDH22 |
|---|---|
| Synonyms | C20orf25 |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues (By similarity). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs.
References
Lewis, J.P., et al. Genomics (2010) In press :
Liu, Y., et al. Cancer Biol. Ther. 8(14):1352-1359(2009)
Zhou, J., et al. Tumour Biol. 30(3):130-140(2009)
Bento, J.L., et al. Genomics 92(4):226-234(2008)
Wu, J., et al. J. Endocrinol. 176(3):381-391(2003)
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