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ARSF Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | P54793 |
| Other Accession | NP_004033.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 65940 Da |
| Antigen Region | 236-264 aa |
| Gene ID | 416 |
|---|---|
| Other Names | Arylsulfatase F, ASF, 316-, ARSF |
| Target/Specificity | This ARSF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-264 amino acids from the Central region of human ARSF. |
| Dilution | FC~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ARSF Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ARSF |
|---|---|
| Function | Exhibits arylsulfatase activity towards the artificial substrate 4-methylumbelliferyl sulfate. |
| Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the sulfatase family, and more specifically, the arylsulfatase subfamily. Members of the subfamily share similarity in sequence and splice sites, and are clustered together on chromosome X, suggesting that they are derived from recent gene duplication events. Sulfatases are essential for the correct composition of bone and cartilage matrix. The activity of this protein, unlike that of arylsulfatase E, is not inhibited by warfarin.
References
Cao, W., et al. J. Biol. Chem. 273(32):20629-20635(1998)
Puca, A.A., et al. Genomics 42(2):192-199(1997)
Parenti, G., et al. Curr. Opin. Genet. Dev. 7(3):386-391(1997)
Franco, B., et al. Cell 81(1):15-25(1995)
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