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FRMD7 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q6ZUT3 |
| Other Accession | NP_919253.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 81614 Da |
| Antigen Region | 115-144 aa |
| Gene ID | 90167 |
|---|---|
| Other Names | FERM domain-containing protein 7, FRMD7 |
| Target/Specificity | This FRMD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-144 amino acids from the N-terminal region of human FRMD7. |
| Dilution | IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FRMD7 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FRMD7 |
|---|---|
| Function | Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability. |
| Cellular Location | Cell projection, neuron projection {ECO:0000250|UniProtKB:A2AD83}. Cell projection, growth cone {ECO:0000250|UniProtKB:A2AD83}. Note=In undifferentiated neurons, located in the actin-rich regions of the cell body. In differentiated neurons, located in the actin-rich regions of the cell body and primary neurite processes but is almost absent from secondary extensions arising from the primary neurite. Also found at the actin-rich distal end of growth cones (By similarity). {ECO:0000250|UniProtKB:A2AD83} |
| Tissue Location | Expressed in liver, kidney, pancreas and at low levels in brain and heart. Expressed in embryonic brain and developing neural retina. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Mutations in this gene are associated with X-linked congenital nystagmus.
References
Fingert, J.H., et al. Ophthalmic Genet. 31(2):77-80(2010)
Betts-Henderson, J., et al. Hum. Mol. Genet. 19(2):342-351(2010)
He, X., et al. Genet. Test. 12(4):607-613(2008)
Thomas, S., et al. Brain 131 (PT 5), 1259-1267 (2008) :
Li, N., et al. Mol. Vis. 14, 733-738 (2008) :
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