SLC27A3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q5K4L6 |
| Other Accession | NP_077306.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 73550 Da |
| Antigen Region | 124-152 aa |
| Gene ID | 11000 |
|---|---|
| Other Names | Long-chain fatty acid transport protein 3, FATP-3, Fatty acid transport protein 3, 621-, Solute carrier family 27 member 3, Very long-chain acyl-CoA synthetase homolog 3, VLCS-3, SLC27A3, ACSVL3, FATP3 |
| Target/Specificity | This SLC27A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human SLC27A3. |
| Dilution | IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SLC27A3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC27A3 (HGNC:10997) |
|---|---|
| Function | Mainly functions as an acyl-CoA ligase catalyzing the ATP- dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates (PubMed:23936004). Can mediate the levels of long-chain fatty acids (LCFA) in the cell by facilitating their transport across membranes (By similarity). |
| Cellular Location | Mitochondrion membrane; Single-pass membrane protein |
| Tissue Location | Expressed in bronchial and bronchiolar epithelial cells (at protein level). |

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Provided below are standard protocols that you may find useful for product applications.
Background
SLC27A3 has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. Does not exhibit fatty acid transport activity (By similarity).
References
Pei, Z., et al. Cancer Res. 69(24):9175-9182(2009)
Pei, Z., et al. J. Biol. Chem. 279(52):54454-54462(2004)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Hirsch, D., et al. Proc. Natl. Acad. Sci. U.S.A. 95(15):8625-8629(1998)
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