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ACTG2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P63267 |
| Other Accession | P63269, P63268, P63270, Q5E9B5, NP_001606.1 |
| Reactivity | Human |
| Predicted | Bovine, Chicken, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 41877 Da |
| Antigen Region | 343-371 aa |
| Gene ID | 72 |
|---|---|
| Other Names | Actin, gamma-enteric smooth muscle, Alpha-actin-3, Gamma-2-actin, Smooth muscle gamma-actin, ACTG2, ACTA3, ACTL3, ACTSG |
| Target/Specificity | This ACTG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-371 amino acids from the C-terminal region of human ACTG2. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ACTG2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ACTG2 |
|---|---|
| Synonyms | ACTA3, ACTL3, ACTSG |
| Function | Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
| Cellular Location | Cytoplasm, cytoskeleton. |
| Tissue Location | In the intestine, abundantly expressed in smooth muscle cells of muscularis mucosa and muscularis propria. Also detected in intestinal vascular smooth muscle cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues.
References
Sun, Q., et al. J. Biol. Chem. 284(47):32582-32590(2009)
Laasanen, J., et al. Fetal. Diagn. Ther. 23(1):36-40(2008)
Goldberg, M.T., et al. J. Invest. Dermatol. 127(11):2645-2655(2007)
Yonemoto, S., et al. Clin. Exp. Nephrol. 10(3):186-192(2006)
Chang, K.W., et al. Hepatol. Res. 36(1):33-39(2006)
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