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ALPPL2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P10696 |
| Other Accession | NP_112603.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 57377 Da |
| Antigen Region | 58-86 aa |
| Gene ID | 251 |
|---|---|
| Other Names | Alkaline phosphatase, placental-like, ALP-1, Alkaline phosphatase Nagao isozyme, Germ cell alkaline phosphatase, GCAP, Placental alkaline phosphatase-like, PLAP-like, ALPPL2, ALPPL |
| Target/Specificity | This ALPPL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of human ALPPL2. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ALPPL2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ALPG (HGNC:441) |
|---|---|
| Function | Alkaline phosphatase that can hydrolyze various phosphate compounds. |
| Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
| Tissue Location | Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors |
Provided below are standard protocols that you may find useful for product applications.
Background
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase.
References
Pelttari, K., et al. Arthritis Rheum. 54(10):3254-3266(2006)
Nakano, T., et al. Biochem. Biophys. Res. Commun. 341(1):33-38(2006)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Le Du, M.H., et al. J. Biol. Chem. 277(51):49808-49814(2002)
Kozlenkov, A., et al. J. Biol. Chem. 277(25):22992-22999(2002)
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