PDCD7 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8N8D1 |
Other Accession | Q9WTY1, NP_005698.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 54700 Da |
Antigen Region | 390-419 aa |
Gene ID | 10081 |
---|---|
Other Names | Programmed cell death protein 7, ES18, hES18, PDCD7 |
Target/Specificity | This PDCD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-419 amino acids from the C-terminal region of human PDCD7. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PDCD7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PDCD7 |
---|---|
Function | Promotes apoptosis when overexpressed. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signalling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.
References
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Will, C.L., et al. RNA 10(6):929-941(2004)
Park, E.J., et al. Nucleic Acids Res. 27(6):1524-1530(1999)
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