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HELT Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | A6NFD8 |
| Other Accession | Q7TS99, Q6QB00, NP_001025058.1 |
| Reactivity | Mouse |
| Predicted | Zebrafish |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 26913 Da |
| Antigen Region | 131-160 aa |
| Gene ID | 391723 |
|---|---|
| Other Names | Hairy and enhancer of split-related protein HELT, HES/HEY-like transcription factor, HELT |
| Target/Specificity | This HELT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-160 amino acids from the Central region of human HELT. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HELT Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HELT |
|---|---|
| Function | Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGCG-3'. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
HELT is a transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGCG-3' (By similarity).
References
Guimera, J., et al. Gene 377, 65-76 (2006) :
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Katoh, M., et al. Int. J. Mol. Med. 14(4):747-751(2004)
Nakatani, T., et al. J. Biol. Chem. 279(16):16356-16367(2004)
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