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ITGB5 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ITGB5 Antibody (N-term) AP14000a
    ITGB5 Antibody (N-term) (Cat. #AP14000a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ITGB5 antibody detected the ITGB5 protein (arrow).
    detail
  • IHC-P - ITGB5 Antibody (N-term) AP14000a
    ITGB5 Antibody (N-term) (Cat. #AP14000a)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ITGB5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • SPECIFICATION
  • CITATIONS: 1
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P18084
Other Accession O70309, P80747, NP_002204.2
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 88054 Da
Antigen Region 216-244 aa
Additional Information
Gene ID 3693
Other Names Integrin beta-5, ITGB5
Target/Specificity This ITGB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-244 amino acids from the N-terminal region of human ITGB5.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsITGB5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ITGB5
Function Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations ( 0 )

Background

Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Li, Z., et al. J. Biol. Chem. 285(31):23699-23710(2010)
Leifheit-Nestler, M., et al. Arterioscler. Thromb. Vasc. Biol. 30(7):1398-1406(2010)
Lane, D., et al. Oncogene 29(24):3519-3531(2010)
Lyle, C., et al. Virol. J. 7, 148 (2010) :

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$ 365.00
$ 140.00
Cat# AP14000a
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