FARSB Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9NSD9 |
| Other Accession | NP_005678.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 66116 Da |
| Antigen Region | 535-564 aa |
| Gene ID | 10056 |
|---|---|
| Other Names | Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS, FARSB, FARSLB, FRSB |
| Target/Specificity | This FARSB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 535-564 amino acids from the C-terminal region of human FARSB. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FARSB Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FARSB |
|---|---|
| Synonyms | FARSLB, FRSB |
| Cellular Location | Cytoplasm. |

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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Finarov, I., et al. Structure 18(3):343-353(2010)
Yu, X.Y., et al. Bioorg. Med. Chem. Lett. 14(5):1339-1342(2004)
Vasil'eva, I.A., et al. Biochemistry Mosc. 69(2):143-153(2004)
Moor, N., et al. Biochemistry 42(36):10697-10708(2003)
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