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HDBP1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - HDBP1 Antibody (Center) AP1422c
    HDBP1 Antibody (Center) (Cat. #AP1422c) western blot analysis in SW620 cell line lysates (35ug/lane).This demonstrates the HDBP1 antibody detected the HDBP1 protein (arrow).
    detail
  • IHC-P - HDBP1 Antibody (Center) AP1422c
    Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with HDBP1 Antibody (Center) (Cat.#AP1422c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
  • SPECIFICATION
  • CITATIONS: 1
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9NR83
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 41267 Da
Antigen Region 213-242 aa
Additional Information
Gene ID 56731
Other Names SLC2A4 regulator, GLUT4 enhancer factor, GEF, Huntington disease gene regulatory region-binding protein 1, HDBP-1, SLC2A4RG, HDBP1
Target/Specificity This HDBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-242 amino acids from the Central region of human HDBP1.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHDBP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC2A4RG
Synonyms HDBP1
Function Transcription factor involved in SLC2A4 and HD gene transactivation. Binds to the consensus sequence 5'-GCCGGCG-3'.
Cellular Location Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus
Tissue Location According to PubMed:14630949, expressed in heart, skeletal muscle, liver, kidney and pancreas; undetectable in lung, placenta or brain. According to PubMed:14625278, ubiquitously expressed, with lowest expression in brain and ileum
Research Areas
Citations ( 0 )

Background

THDBP1 is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. This protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene.

References

Jones,M.R., Fertil. Steril. (2008)
McGee,S.L., FASEB J. 20 (2), 348-349 (2006)
Tanaka,K., J. Biol. Chem. 279 (8), 7275-7286 (2004)

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$ 365.00
$ 140.00
Cat# AP1422c
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