Mapk3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q63844, P21708 |
| Other Accession | NP_036082.1 |
| Reactivity | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Antigen Region | 353-380 aa |
| Other Names | Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, MNK1, Microtubule-associated protein 2 kinase, p44-ERK1, Mapk3, Erk1, Prkm3 |
|---|---|
| Target/Specificity | This Mapk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-380 amino acids from the C-terminal region of mouse Mapk3. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mapk3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |

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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2) and heat shock factor protein 4 (HSF4) (By similarity). Phosphorylates SPZ1.
References
Chen, W., et al. Biochem. Biophys. Res. Commun. 401(3):339-343(2010)
Chandrakesan, P., et al. J. Biol. Chem. 285(43):33485-33498(2010)
Alter, B.J., et al. J. Neurosci. 30(34):11537-11547(2010)
Spruce, T., et al. Dev. Cell 19(2):207-219(2010)
Bremer, J., et al. PLoS ONE 5 (8), E12450 (2010) :
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