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Mouse Nek4 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Z1J2 |
| Other Accession | P51957, NP_035979.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 88994 Da |
| Antigen Region | 74-101 aa |
| Gene ID | 23955 |
|---|---|
| Other Names | Serine/threonine-protein kinase Nek4, Never in mitosis A-related kinase 4, NimA-related protein kinase 4, Serine/threonine-protein kinase 2, Nek4, Stk2 |
| Target/Specificity | This Mouse Nek4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-101 amino acids from the N-terminal region of mouse Nek4. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Nek4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Nek4 |
|---|---|
| Synonyms | Stk2 |
| Function | Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence. Required for normal cell cycle arrest in response to double-stranded DNA damage (By similarity). Protein kinase that seems to act exclusively upon threonine residues. |
| Cellular Location | Cytoplasm. Cell projection, cilium {ECO:0000250|UniProtKB:P51957} |
| Tissue Location | Expressed ubiquitously among various organs and is up-regulated in the testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Nek4 seems to act exclusively upon threonine residues.
References
Doles, J., et al. Cancer Res. 70(3):1033-1041(2010)
Forrest, A.R., et al. Genome Res. 13 (6B), 1366-1375 (2003) :
Hayashi, K., et al. Biochem. Biophys. Res. Commun. 264(2):449-456(1999)
Chen, A., et al. Gene 234(1):127-137(1999)
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