FOXP4 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q8IVH2 |
| Other Accession | Q9DBY0, NP_001012426.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 73488 Da |
| Antigen Region | 522-550 aa |
| Gene ID | 116113 |
|---|---|
| Other Names | Forkhead box protein P4, Fork head-related protein-like A, FOXP4, FKHLA |
| Target/Specificity | This FOXP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 522-550 amino acids from the C-terminal region of human FOXP4. |
| Dilution | IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FOXP4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FOXP4 |
|---|---|
| Synonyms | FKHLA |
| Function | Transcriptional repressor that represses lung-specific expression. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089}. |

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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq].
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Takata, R., et al. Nat. Genet. 42(9):751-754(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Tuovinen, H., et al. J. Immunol. 180(6):3651-3654(2008)
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