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Mouse Map2k3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O09110 |
| Other Accession | NP_032954.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 39296 Da |
| Antigen Region | 132-160 aa |
| Gene ID | 26397 |
|---|---|
| Other Names | Dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, MAPKK 3, MAPK/ERK kinase 3, MEK 3, Map2k3, Mkk3, Prkmk3 |
| Target/Specificity | This Mouse Map2k3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the Central region of mouse Map2k3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Map2k3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Map2k3 |
|---|---|
| Synonyms | Mkk3, Prkmk3 |
| Function | Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38 (By similarity).
References
Yang, Z., et al. J. Immunol. 185(10):6205-6213(2010)
Remy, G., et al. Cell. Signal. 22(4):660-667(2010)
Behren, A., et al. Oncogene 29(10):1519-1530(2010)
Nagelin, M.H., et al. J. Biol. Chem. 284(45):31303-31314(2009)
Yoshizawa, T., et al. J. Immunol. 183(2):1360-1367(2009)
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