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KIF5C Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O60282 |
| Other Accession | P28738, NP_004513.1 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 109495 Da |
| Antigen Region | 758-786 aa |
| Gene ID | 3800 |
|---|---|
| Other Names | Kinesin heavy chain isoform 5C, Kinesin heavy chain neuron-specific 2, KIF5C, KIAA0531, NKHC2 |
| Target/Specificity | This KIF5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 758-786 amino acids from the C-terminal region of human KIF5C. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KIF5C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KIF5C |
|---|---|
| Synonyms | KIAA0531, NKHC2 |
| Function | Microtubule-associated force-producing protein that may play a role in organelle transport. Has ATPase activity (By similarity). Involved in synaptic transmission (PubMed:24812067). Mediates dendritic trafficking of mRNAs (By similarity). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton. Cell projection, dendrite. Note=Abundant in distal regions of dendrites. |
| Tissue Location | Highest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Wang, X., et al. Cell 136(1):163-174(2009)
Schafer, B., et al. Cell. Mol. Life Sci. 66(2):339-349(2009)
Schafer, B., et al. Biochem. Biophys. Res. Commun. 375(2):179-183(2008)
Cho, K.I., et al. Traffic 8(12):1722-1735(2007)
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