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Latexin Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, FC, WB, E |
|---|---|
| Primary Accession | Q9BS40 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 25750 Da |
| Antigen Region | 78-107 aa |
| Gene ID | 56925 |
|---|---|
| Other Names | Latexin, Endogenous carboxypeptidase inhibitor, ECI, Protein MUM, Tissue carboxypeptidase inhibitor, TCI, LXN |
| Target/Specificity | This Latexin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-107 amino acids from the Central region of human Latexin. |
| Dilution | IHC-P~~1:10~50 FC~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Latexin Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LXN |
|---|---|
| Function | Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Latexin possesses nearly irreversible, non-competitive and potent inhibition of zinc-dependent metallocarboxypeptidases CPA1, CPA2, and CPA4. It is expressed in a neuronal subset in the cerebral cortex and cells in other neural and non-neural tissues of rat. Latexin plays a role in regional specification and/or morphogenesis of the forebrain.
References
Pallares,I., Proc. Natl. Acad. Sci. U.S.A. 102 (11), 3978-3983 (2005)
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