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ANKS4B Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8N8V4 |
| Other Accession | NP_665872.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 46597 Da |
| Antigen Region | 184-213 aa |
| Gene ID | 257629 |
|---|---|
| Other Names | Ankyrin repeat and SAM domain-containing protein 4B, Harmonin-interacting ankyrin repeat-containing protein, Harp, ANKS4B, HARP |
| Target/Specificity | This ANKS4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-213 amino acids from the Central region of human ANKS4B. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ANKS4B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ANKS4B (HGNC:26795) |
|---|---|
| Function | As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. Plays a role in assembly of the complex (PubMed:26812018). May play a role in cellular response to endoplasmic reticulum stress (By similarity). |
| Cellular Location | Cell projection, microvillus Note=Localizes at the tip of microvilli (PubMed:26812018, PubMed:32209652). May associate with endoplasmic reticulum membranes (By similarity). {ECO:0000250|UniProtKB:Q8K3X6, ECO:0000269|PubMed:26812018, ECO:0000269|PubMed:32209652} |
| Tissue Location | Expressed in kidney and small intestine. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Johnston, A.M., et al. Genes Cells 9(10):967-982(2004)
Weil, D., et al. Hum. Mol. Genet. 12(5):463-471(2003)
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