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BDP (ARID3B) Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q8IVW6 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 60637 Da |
| Antigen Region | 409-439 aa |
| Gene ID | 10620 |
|---|---|
| Other Names | AT-rich interactive domain-containing protein 3B, ARID domain-containing protein 3B, Bright and dead ringer protein, Bright-like protein, ARID3B, BDP, DRIL2 |
| Target/Specificity | This BDP (ARID3B) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human BDP (ARID3B). |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BDP (ARID3B) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ARID3B |
|---|---|
| Synonyms | BDP, DRIL2 |
| Function | Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355, ECO:0000269|PubMed:10446990, ECO:0000269|PubMed:17400556} |
| Tissue Location | Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K-562 erythrocytic leukemia cell line (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
ARIDB3 is a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. This protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification.
References
Kortschak,R.D., Trends Biochem. Sci. 25 (6), 294-299 (2000)
Numata,S., Cancer Res. 59 (15), 3741-3747 (1999)
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