UTS2R Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q9UKP6 |
| Other Accession | NP_061822.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 42130 Da |
| Antigen Region | 223-252 aa |
| Gene ID | 2837 |
|---|---|
| Other Names | Urotensin-2 receptor, UR-2-R, G-protein coupled receptor 14, Urotensin II receptor, UR-II-R, UTS2R, GPR14 |
| Target/Specificity | This UTS2R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-252 amino acids from the Central region of human UTS2R. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UTS2R Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UTS2R |
|---|---|
| Synonyms | GPR14 |
| Function | High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Most abundant expression in the heart and pancreas. |

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Provided below are standard protocols that you may find useful for product applications.
Background
High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
References
Gould, P.S., et al. Hypertension 56(1):172-178(2010)
Liu, D., et al. Int. J. Mol. Med. 25(6):845-851(2010)
d'Emmanuele di Villa Bianca, R., et al. J Sex Med 7(5):1778-1786(2010)
Papadopoulos, P., et al. Atherosclerosis 204(2):395-404(2009)
Giuliani, L., et al. J. Clin. Endocrinol. Metab. 94(2):684-690(2009)
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