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Mouse Rps6kb2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Z1M4 |
| Other Accession | NP_067460.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 53538 Da |
| Antigen Region | 318-346 aa |
| Gene ID | 58988 |
|---|---|
| Other Names | Ribosomal protein S6 kinase beta-2, S6K-beta-2, S6K2, 70 kDa ribosomal protein S6 kinase 2, p70 ribosomal S6 kinase beta, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, Rps6kb2 |
| Target/Specificity | This Mouse Rps6kb2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-346 amino acids from the C-terminal region of mouse Rps6kb2. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Rps6kb2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Rps6kb2 |
|---|---|
| Function | Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7. |
| Cellular Location | Cytoplasm. Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphorylates specifically ribosomal protein S6.
References
Lai, K.P., et al. EMBO J. 29(17):2994-3006(2010)
Michels, A.A., et al. Mol. Cell. Biol. 30(15):3749-3757(2010)
Alain, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(4):1576-1581(2010)
Pastor, M.D., et al. J. Biol. Chem. 284(33):22067-22078(2009)
Kroczynska, B., et al. Mol. Cell. Biol. 29(10):2865-2875(2009)
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