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KLK12 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UKR0 |
| Other Accession | NP_062544.1, NP_665901.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 26734 Da |
| Antigen Region | 85-113 aa |
| Gene ID | 43849 |
|---|---|
| Other Names | Kallikrein-12, 3421-, Kallikrein-like protein 5, KLK-L5, KLK12, KLKL5 |
| Target/Specificity | This KLK12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-113 amino acids from the Central region of human KLK12. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KLK12 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KLK12 |
|---|---|
| Synonyms | KLKL5 |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq].
References
Klein, R.J., et al. Cancer Prev Res (Phila) 3(5):611-619(2010)
Memari, N., et al. Biol. Chem. 388(4):427-435(2007)
Lundwall, A., et al. Biol. Chem. 387(6):637-641(2006)
Shinmura, K., et al. Hum. Mutat. 24(3):273-274(2004)
Grimwood, J., et al. Nature 428(6982):529-535(2004)
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