STX6 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | O43752 |
Other Accession | NP_005810.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 29176 Da |
Antigen Region | 121-149 aa |
Gene ID | 10228 |
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Other Names | Syntaxin-6, STX6 |
Target/Specificity | This STX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-149 amino acids from the Central region of human STX6. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | STX6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | STX6 |
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Function | SNARE promoting movement of transport vesicles to target membranes. Targets endosomes to the trans-Golgi network, and may therefore function in retrograde trafficking. Together with SNARE STX12, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway. |
Cellular Location | Golgi apparatus membrane; Single-pass type IV membrane protein. Golgi apparatus, trans-Golgi network membrane {ECO:0000250|UniProtKB:Q63635}; Single-pass type IV membrane protein. Recycling endosome membrane {ECO:0000250|UniProtKB:Q63635}; Single-pass type IV membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
STX6 is involved in intracellular vesicle trafficking.
References
Cheng, J., et al. Mol. Biol. Cell 21(7):1178-1187(2010)
Zhang, Y., et al. J. Biol. Chem. 283(45):30689-30698(2008)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Nakamura, N., et al. Mol. Biol. Cell 16(4):1696-1710(2005)
Huynh, H., et al. Nat. Cell Biol. 6(9):831-839(2004)
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